Transgenics

Guidelines for Transgenic Research

Canadian Council on Animal Care- guidelines for transgenic animals are provided: to assist Animal Care Committee (ACC) members and investigators in evaluating the ethical and technological aspects of the proposed creation, care and use of transgenic animals.
www.ccac.ca/en/CCAC_Programs/Guidelines_Policies/GDLINES/TRANSGEN/TRANSGE1.HTM

Model animals for biomedical research

This is a web site that has been developed by the National Institutes of Health and provides information about national and international activities and major resources that are being developed to facilitate biomedical research using the animal models listed here. Species include mouse, rat and non-mammalians models in the round worm fruit fly, zebra fish and frog.
www.nih.gov/science/models/

Transgenic animal web

This site that has links to useful resources. It has been developed by the University of Michigan and includes a very useful guide to searching the web for mouse models of human disease and genetically altered mouse strains.
www.med.umich.edu/tamc/links.html

Refinement and reduction in production of genetically modified mice

This is the sixth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement and is published as a supplement to Laboratory Animals (Volume 37, Supplement 1, July 2003).  This fifty-page report covers the techniques and stages involved in the production of GM mice, tissue biopsy techniques, identification methods, assessment of animal welfare, reducing the numbers of surplus mice, and strategies to refine these procedures.

For further information go to:
http://www.rspca.org.uk/sciencegroup/researchanimals/implementing3rs/refinement